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All times are CEST (UTC + 2)
| Bilbao – Cadiz | 0:1 (end) | | | Sevilla – Levante | 1:0 (end) | | | Celta Vigo – Barcelona | 0:3 (end) |
| Granada – Osasuna | 0:0 (post.) |
| Aston Villa – Stoke | 0:1 (end) | | | Liverpool – Arsenal | 0:0 (4:5 after SO) |
| Kluž – KuPS | 3:1 (end) | | | Ararat-Armenia – CZ Bělehrad | 1:2 (end) | | | Dinamo Zagreb – Flora | 3:1 (end) |
| Liberec – APOEL | 1:0 (end) | | | Malmö – Granada | 1:3 (end) | | | Charleroi – Lech Poznań | 1:2 (end) |
| Rosenborg – Eindhoven | 0:2 (end) | | | Be'er Sheva – Plzeň | 1:0 (end) | | | Legia – Qarabağ FK | 0:3 (end) |
| FK Sarajevo – Celtic | 0:1 (end) | | | Dinamo Brest – Ludogorec | 0:2 (end) | | | Standard – Fehérvár | 3:1 (end) |
| København – Rijeka | 0:1 (end) | | | Dundalk – KÍ Klaksvík | 3:1 (end) | | | Young Boys – Tirana | 3:0 (end) |
| Basel – CSKA Sofia | 1:3 (end) | | | Rangers – Galatasaray AŞ | 2:1 (end) | | | AEK Atény – Wolfsburg | 2:1 (end) |
| Sporting – Linz | 1:4 (end) | | | Rio Ave – AC Milan | 2:2 (8:9 after SO) | | | Tottenham – Maccabi Haifa | 7:2 (end) |
postponed
Granada CF
0:0
(-:-)
CA Osasuna
|
90
|
Domingos Duarte (Granada CF) is shown a yellow card.
|
|
|
76
|
Enric Gallego (CA Osasuna) is shown a yellow card.
|
|
|
67
|
David García (CA Osasuna) is shown a yellow card.
|
|
|
40
|
Rubén García (CA Osasuna) is shown a yellow card.
|
|
|
35
|
Oier (CA Osasuna) is shown a yellow card.
|
Goals:
Referees:
Attendance:
Penalty missed:
Granada CF:
Subs:
Coach:
CA Osasuna:
Subs:
Coach:
Subs:
Coach:
CA Osasuna:
Subs:
Coach:
Referees:
Attendance: